Protein based antigen can save humanity from Covid-19

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There is good news on Covid-19 findings over cures...


According to the American Chemical Society, researchers have found a protein that can create a layer of immunisation against the SARS-Cov-2 virus aka the Covid-19 carrying virus. By immunising mice, they have found that the proteins' nanoparticles can mimic SARS-CoV-2 by displaying multiple copies of the receptor binding domain (RBD) antigen.

The findings on their protein-based vaccine have been published in ACS Central Science.

The team has been able to make nanoparticles similar in size to SARS-CoV-2 and further decorated them with many RBDs. This formula was then injected into mice, along with separate nanoparticles containing an adjuvant, in two doses three weeks apart.

For comparison, they immunised another group of mice with polymersomes that encapsulated the RBD, along with the nanoparticles containing the adjuvant. Although both groups of mice produced high levels of RBD-specific antibodies, only the surface-decorated nanoparticles generated neutralising antibodies that prevented SARS-CoV-2 infection in cells.


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